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Drug Counseling and Fermagenetics

About Unit

What is Drug Counseling and Fermagenetics?

It has been known for centuries that there are significant differences in the response of the patient to the drug in patients who are treated with drugs. It is aimed to draw attention to the individual differences that can be observed during the disease process or treatment with the phrase, "A good doctor treats the disease, and a better doctor treats the patient", which is accepted by the medical community all over the world.

Patients with the same diagnosis and similar biological and environmental factors may respond differently to treatment despite using the same drugs at the same doses. A drug may cure one patient's illness but not another's. It may even show toxic side effects in some patients. For these observations, it is not essential that what we take is medicine, the same may be the case with some foods, some people get gas when they touch milk, and some get diarrhea when they eat fish. These are events that we encounter frequently in our daily lives.

These differences in drug response among patients are not to be underestimated. Only 60-70% of patients respond to standard treatments and recover. The remaining 30-40% of patients have to apply to health institutions again on the grounds that this drug does not help or the drug touches them. These differences have caused the phrase 'there is no disease, there is a patient' to become a motto in the medical community. In other words, everyone's illness and treatment is unique to him.

The reasons for these differences between patients have been investigated for many years. Many factors such as the patient's age, lifestyle, other drugs he uses, other diseases he carries, eating and drinking habits change the effect of the drug, but the most important among them is the genetic differences of the person. Our genetic makeup has minor differences that make us different from one another. These small changes, called Single Nucleotide Polymorphism (SNP), make up our individual differences. That's why we all have fingerprints, eyes, voice, etc. are different from each other. Likewise, we give different responses to drugs because of the SNPs found in our organs and tissues that the drugs we take encounter during their journey in the body. That's why everyone has their own illness.

This is called 'Individual Medicine' or 'Personalized Medicine' in the medical literature. Likewise, everyone's medicine, the dose of the medicine and how to use it show personal differences. This is also called 'Individual Medicine (Treatment)' or 'Personalized Medicine (Treatment)' in the medical literature. In order to achieve this, people need to use the drug appropriate for their genetic structure in the appropriate dose. To abandon the approach of 'let's start the medicine for you, we will increase the dose according to your answer' or 'we will start this medicine, if we do not get a response or if we see side effects, we will change it' approach, which has been used until now, some genetic studies have been carried out in order to be able to treat patients with a new approach in the scientific light of pharmacogenetic tests. tests should be done and the person should be treated in the light of these tests. These tests allow patients to quickly find the appropriate drug and the appropriate dose without resorting to trial and error. The science of Pharmacogenetics, which reveals the effect of the genetic structure of the individual on the drugs he/she is using/will use, as long as he/she will spend in the organism, reveals the role of genetic differences in the response to the drug and ensures that the most appropriate treatment is given to the patient at the most appropriate dose and at the most appropriate time.

Drug Counseling and Pharmacogenetics Polyclinic is a polyclinic where the causes of these problems related to drug therapy are investigated and new and beneficial treatment options are presented to the patient group who do not respond to treatment or have very severe side effects during treatment.

Who Can Apply to the Drug Counseling and Pharmacogenetics Polyclinic?

  • Patients who do not respond to treatment
  • Patients with aggravated side effects during treatment
  • Patients with toxic symptoms during treatment
  • Patients over 65 years of age
  • Children under 16 years of age
  • Pregnant women
  • Patients with other concomitant chronic diseases (heart disease, high blood pressure, diabetes, etc.)
  • Patients using multiple drugs

What Does Applying to the Drug Counseling and Pharmacogenetics Polyclinic Gain the Patient?

  • The treatment chosen based on scientific data will not waste the patient's time, thus preventing the disease from progressing and becoming chronic.
  • Financial losses due to unsuccessful treatment, repeated visits to the doctor, prescription costs, hospitalizations, and other medical tests to be performed will be eliminated.
  • The patient will get maximum efficiency from the chosen treatment, and the side effects that may occur in the patient will be minimized.
  • The patient will not suffer the loss of labor due to the prolongation of the treatment.
  • As a result of the examinations, the reason for the patient's complaints such as unresponsiveness to the drug, excessive reaction or excessive side effects will be understood, and the most appropriate drug combinations that can produce maximum effect and minimum side effects will be recommended to the patient.

Unit Doctors

Esra Küsdül Sağlam

Prof. Dr. Esra Küsdül Sağlam

Drug Counseling and Fermagenetics

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Tuğba Gümüştaş

Asst. Prof. Dr. Tuğba Gümüştaş

Drug Counseling and Fermagenetics

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